Neurocognitive and neurodegenerative diseases are disorders of the brain that cause a wide range of problems, including memory loss, movement, and breathing difficulties. They can be devastating to a person’s quality of life.
Biological aging processes interact with CNS changes to contribute to cognitive decline, neuropathological protein accumulation, and brain morphology changes. Understanding these interactions is important for developing effective therapeutic strategies.
Alzheimer’s Disease
Alzheimer’s Disease is a disorder of the brain that causes memory loss and other problems with thinking, learning, and behavior. It is caused by a loss of nerve cells, or neurons, in the brain. These neurons are surrounded by plaques and tangles. Like all other nootropic medicines, the purpose of Modvigil 200 Buy Online tablets is to improve cognition, memory, and alertness.
As Alzheimer’s progresses, short-term memory is often the first to be lost, but other functions and abilities also deteriorate over time. Language, attention, judgment, and many other aspects of thinking and behavior are affected.
The symptoms of Alzheimer’s Disease vary from person to person. Generally, they appear around the age of 60 and worsen over time.
There is no cure for Alzheimer’s Disease, but medications can help stabilize or slow the decline in memory and thinking ability. These drugs work by curbing the breakdown of a chemical in the brain called acetylcholine. This may slow how quickly the condition gets worse for about half of the people who take them.
Parkinson’s Disease
A person with Parkinson’s disease can experience a variety of symptoms, including body tremors (rhythmic shaking), slow movement (bradykinesia), stiff muscles, and changes in facial expression. These signs and symptoms can vary from person to person but are typically more severe in the later stages of Parkinson’s disease.
A tremor, or rhythmic shaking, often begins in the hand or fingers. It can begin at rest and increase as you move your hand, or it may decrease during a task.
Slowed movements (bradykinesia) occur over time and can make simple tasks difficult, such as walking. It also makes sitting up from a chair more difficult and causes you to drag or shuffle your feet.
Changes in the quality and volume of your voice are another early sign of Parkinson’s. A softer or lower voice is common.
The ability to make facial expressions is also often affected, causing a person to appear blank or emotionless. This is called facial masking.
Huntington’s Disease
Huntington’s Disease is a genetic disorder that causes changes in the central part of the brain. It affects movement, mood, and thinking skills. Artvigil 150 Australia, a wake-promoting and cognitive-enhancing drug has been considered as a treatment for HD.
People with this condition usually develop symptoms in their mid-30s to 40s. The disease does cause by a change (mutation) in the gene for huntingtin, which carries instructions for producing a protein called HTT.
The mutated gene contains abnormally long repeats of the coded chemical cytosine, adenine and guanine (CAG trinucleotide repeat expansion). The length of the expanded repeats may be different for people with this condition.
Symptoms of HD include uncontrolled movements and problems with planning and memory. Symptoms also can include changes in mood, such as depression or anger.
Huntington’s is an autosomal dominant disorder, which means that a person who inherits a gene mutation from one parent has a 50% chance of developing the disease. Men and women are equally likely to have this disorder.
Dementia with Lewy Bodies
Dementia with Lewy Bodies is a type of dementia that’s characterize by the buildup of abnormal clumps of protein in the brain call Lewy bodies. They’re similar to the plaques and tangles that form in the brains of people with Alzheimer’s disease.
These clumps break down and destroy nerve cells in the brain, causing the symptoms of LBD. They also may cause problems with thinking and movement, affecting an individual’s ability to function.
Early symptoms of LBD can include changes in attention, concentration, alertness, and sleep. These can occur throughout the day or change from moment to moment.
They can be accompanied by hallucinations or disorganized speech. These changes can be frightening or distressing, but they’re usually not life-threatening.
Some doctors may prescribe antipsychotic medications, or neuroleptics, to treat these symptoms. But these drugs can sometimes make LBD symptoms worse, and they can be dangerous if used too long or in high doses.
